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Giant negative T waves in Guillain–Barré syndrome

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A Guillain–Barré syndrome patient showed giant negative T waves on electro‐cardiography at the height of the disease, with large left ventricular hypokinesis on echocardiography and extensive defects on 123I‐meta‐iodobenzylguanidine myocardial scintigraphy. Gamma‐globulin improved the neurological symptoms, and the above abnormalities resolved. We speculate that cardiac sympathetic nerve endings were transiently damaged, with consequent myocardial injury, due to norepinephrine toxicity.
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Keywords: 123I‐MIBG myocardial scintigraphy; Guillain–Barré syndrome; electrocardiography; giant negative T waves

Document Type: Research Article

Affiliations: 1: Neurology and 2: Cardiology, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259–1193, Japan

Publication date: 2000-03-01

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