Prevalence of symptoms of asthma, rhinitis and eczema in 13- to 14-year-old children in Africa: the International Study of Asthma and Allergies in Childhood Phase III
Authors: Ait-Khaled, N.1; Odhiambo, J.2; Pearce, N.3; Adjoh, K. S.4; Maesano, I. A.5; Benhabyles, B.6; Bouhayad, Z.7; Bahati, E.8; Camara, L.9; Catteau, C.10; El Sony, A.11; Esamai, F. O.12; Hypolite, I. E.13; Melaku, K.14; Musa, O. A.15; Ng'ang'a, L.16; Onadeko, B. O.17; Saad, O.15; Jerray, M.18; Kayembe, J. M.19; Koffi, N. B.20; Khaldi, F.21; Kuaban, C.22; Voyi, K.23; M'Boussa, J.24; Sow, O.25; Tidjani, O.26; Zar, H. J.27
Source: Allergy, Volume 62, Number 3, March 2007 , pp. 247-258(12)
Publisher: Blackwell Publishing
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Abstract:
Phase I of the International Study of Asthma and Allergies in Childhood has provided valuable information regarding international prevalence patterns and potential risk factors in the development of asthma, allergic rhinoconjunctivitis and eczema. However, in Phase I, only six African countries were involved (Algeria, Tunisia, Morocco, Kenya, South Africa and Ethiopia). Phase III, conducted 5-6 years later, enrolled 22 centres in 16 countries including the majority of the centres involved in Phase I and new centres in Morocco, Tunisia, Democratic Republic of Congo, Togo, Sudan, Cameroon, Gabon, Reunion Island and South Africa. There were considerable variations between the various centres of Africa in the prevalence of the main symptoms of the three conditions: wheeze (4.0-21.5%), allergic rhinoconjunctivitis (7.2-27.3%) and eczema (4.7-23.0%). There was a large variation both between countries and between centres in the same country. Several centres, including Cape Town (20.3%), Polokwane (18.0%), Reunion Island (21.5%), Brazzaville (19.9%), Nairobi (18.0%), Urban Ivory Coast (19.3%) and Conakry (18.6%) showed relatively high asthma symptom prevalences, similar to those in western Europe. There were also a number of centres showing high symptom prevalences for allergic rhinoconjunctivitis (Cape Town, Reunion Island, Brazzaville, Eldoret, Urban Ivory Coast, Conakry, Casablanca, Wilays of Algiers, Sousse and Eldoret) and eczema (Brazzaville, Eldoret, Addis Ababa, Urban Ivory Coast, Conakry, Marrakech and Casablanca).Keywords: Africa; asthma; children; eczema; ISAAC; rhinitis
Document Type: Research article
DOI: 10.1111/j.1398-9995.2007.01325.x
Affiliations: 1: International Union Against Tuberculosis and Lung Disease, Paris, France (ISAAC Regional Coordinator for Africa `French-speaking' countries) 2: CDC/GAP, Nairobi, Kenya (ISAAC Regional Coordinator for Africa `English-speaking' countries) 3: Centre for Public Health Research, Massey University, Wellington, New Zealand (ISAAC Executive Committee) 4: University Hospital of Lome, Togo ISAAC Principal Investigator Lome (Togo): 5: EPAR, U707 INSERM, Paris, France; UMR-S 707 UPMC Paris 6, Paris, France; Medical School St-Antoine National coordinator, Reunion Island (Reunion Island) 6: Centre Hospitalo Universitaire Mustapha, Algiers, Algeria Principal Investigator Algiers (Algeria): 7: Centre Hospitalo Universitaire, Casablanca, Morocco (Principal Investigator Benislimane, Boulmene, Casablanca, Marrakech (Morocco) 8: National Tuberculosis Program, Kinshasa, Democratic Republic of Congo ISAAC National Coordinator Kinshasa (Democratic Republic of Congo): 9: Centre Hospitalo Univeristaire Ignace Deen, Conakry, Guinea ISAAC National Coordinator Conakry (Guinea): 10: DRASS, St Denis, Principal Investigator, Reunion Island: 11: Epilab Director, AMST, EPILAB, Khartoum (Sudan) National Coordinator Khartoum (Sudan): 12: Department of Child Health and Paediatrics, Moi University Principal Investigator Eldoret (Kenya): 13: Hôpital Régional de Port-Gentil, Port-Gentil, Gabon Principal Investigator Port Gentil (Gabon): 14: Department of Internal Medicine, Faculty of Medicine, Addis Ababa University, Ethiopia Principal Investigator Addis Ababa (Ethiopia): 15: Faculty of Medicine, National Ribat University Principal Investigator Khartoum (Sudan): 16: Centres for Disease Control & Prevention (CDC) Principal Investigator Nairobi (Kenya): 17: Department of Medicine, University College Hospital Principal Investigator Ibadan (Nigeria): 18: Centre Hospitalo Universitaire, Sousse, Tunisia (Principal Investigator Sousse) 19: Centre Hospitalo Universitaire, Kinshasa Principal Investigator Kinshasa (Democratic Republic of Congo): 20: Hôpital de Cocody, Abidjan, Ivory Coast (Principal Investigator Urban Ivory Coast) 21: Hôpital d'Enfants, Tunis Jebbari, Tunisia (Principal Investigator Grand Tunis) 22: Hôpital Jamot, Yaounde, Cameroon (ISAAC Principal Investigator Yaounde) 23: Centre Hospitalo Universitaire, Brazzaville, Congo (ISAAC Principal Investigator Brazzaville) 24: Department of Environmental and Occupational Health, School of Health Systems and Public Health, University of Pretoria, South Africa 25: Centre Hospitalo Universitaire Ignace Deen, Conakry, Guinea ISAAC National Coordinator Conakry (Guinea): 26: Centre Hospitalo Universitaire, Lome, Togo (ISAAC National Coordinator Lome) 27: Red Cross Children's Hospital, University of Cape Town (Principal Investigator Cape Town), Cape Town, South Africa
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