Serine proteases, their inhibitors and allergy

Authors: Smith, P. K.¹; Harper, J. I.²

Source: Allergy, Volume 61, Number 12, December 2006 , pp. 1441-1447(7)

Publisher: Blackwell Publishing

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Abstract:

This paper reviews four serine protease inhibitors and three protease gene defects that are associated with allergic conditions, suggesting an important role for these genes and their products in the development of allergy. Serine protease inhibitors may have a therapeutic potential in the treatment of allergy.

Keywords: allergy; proteases; serine protease inhibitors

Document Type: Research article

DOI: 10.1111/j.1398-9995.2006.01233.x

Affiliations: 1: Bond University Medical School, Robina, Australia 2: Great Ormond St Hospital for Children, London, UK

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