Home >> American Journal of Transplantation, Volume 9, Number 3

Free Content Racial Disparity Trends for Graft Failure in the US Pediatric Kidney Transplant Population, 1980-2004

Authors: Chavers, B. M.; Snyder, J. J.; Skeans, M. A.; Weinhandl, E. D.; Kasiske, B. L.

Source: American Journal of Transplantation, Volume 9, Number 3, March 2009 , pp. 543-549(7)

Publisher: Wiley-Blackwell

Buy & download fulltext article:

You have access to the full text article on a website external to ingentaconnect.

Please click here to view this article on Wiley Online Library.

You may be required to register and activate access on Wiley Online Library before you can obtain the full text. If you have any queries please visit Wiley Online Library

Abstract:

Graft survival among adult African American kidney transplant patients remains low compared to whites, but little information is available for children and adolescents. We examined trends in graft failure among US incident primary kidney transplant patients aged <19 years (n = 13 692), 1980-2004. Trends in 1-year and 2- to 5-year graft failure (for patients whose grafts survived the first year) were analyzed in 5-year intervals. One-year graft failure declined 70% for white and 77% for African American patients over the 25-year period, and 1-year graft failure rates improved at a slightly higher rate for African American compared to white patients (p = 0.02). In contrast, the graft failure rates for years 2-5 declined 53% for white and only 41% for African American patients over the 25 years (p = 0.29). In fully adjusted Cox proportional hazards analysis, the rate of graft failure among African Americans was approximately 2-fold higher than for white patients over the entire study period. Graft survival has improved slightly more for African American than white pediatric patients over the past 25 years. However, graft survival for African American pediatric patients remains poor compared with white patients.

Keywords: End-stage renal disease; kidney transplantation; pediatric

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1600-6143.2008.02530.x

Affiliations: 1: United States Renal Data System, Minneapolis, MN

Publication date: 2009-03-01

Related content
Marked list

Tools

Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content

Text size:

A | A | A | A
^ Back to top
Share this item with others: These icons link to social bookmarking sites where readers can share and discover new web pages. print icon Print this page