Skip to main content

A history of childhood attention-deficit hyperactivity disorder (ADHD) impacts clinical outcome in adult bipolar patients regardless of current ADHD

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

Rydén E, Thase ME, Stråht D, Åberg-Wistedt A, Bejerot S, Landén M. A history of childhood attention-deficit hyperactivity disorder (ADHD) impacts clinical outcome in adult bipolar patients regardless of current ADHD. Objective: 

The occurrence of comorbid attention-deficit hyperactivity disorder (ADHD) might have an impact of the course of the bipolar disorder. Method: 

Patients with bipolar disorder (n = 159) underwent a comprehensive evaluation with respect to affective symptoms. Independent psychiatrists assessed childhood and current ADHD, and an interview with a parent was undertaken. Results: 

The prevalence of adult ADHD was 16%. An additional 12% met the criteria for childhood ADHD without meeting criteria for adult ADHD. Both these groups had significantly earlier onset of their first affective episode, more frequent affective episodes (except manic episodes), and more interpersonal violence than the bipolar patients without a history of ADHD. Conclusion: 

The fact that bipolar patients with a history of childhood ADHD have a different clinical outcome than the pure bipolar group, regardless of whether the ADHD symptoms remained in adulthood or not, suggests that it represent a distinct early-onset phenotype of bipolar disorder.

Keywords: attention-deficit disorder; bipolar disorder; classification; comorbidity; phenotype

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1600-0447.2009.01399.x

Affiliations: 1: Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden 2: University of Pennsylvania School of Medicine and the Veterans Affairs Medical Center, Philadelphia, PA, USA

Publication date: 2009-09-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more