Skip to main content

The association between cognition and functional outcome in first-episode patients with schizophrenia: mystery resolved?

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

van Winkel R, Myin-Germeys I, De Hert M, Delespaul P, Peuskens J, van Os J. The association between cognition and functional outcome in first-episode patients with schizophrenia: mystery resolved? Objective: 

The presence of a prospective association between cognition and functional outcome in first episode patients with schizophrenia is much debated. Method: 

Associations between Intelligence Quotient (IQ) measures and functional outcome were assessed at the first hospitalization and after 10 years follow-up. Results: 

Functional outcome was associated with estimated premorbid IQ and IQ at 10-year follow-up, but not with IQ assessed at first hospitalization. Conclusion: 

The presence of a prospective as well as a cross-sectional relationship of the global cognitive measure IQ with 10-year functional outcome could be established. However, assessing associations between cognitive measures assessed at first hospitalization and subsequent functional outcome, can give inconclusive results due to non-uniform intellectual deterioration from premorbid level in the period preceding the first hospitalization.

Keywords: Intelligence; outcomes research; schizophrenia

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1600-0447.2007.01014.x

Affiliations: 1: Department of Psychiatry and Neuropsychology (DRT10), European Graduate School of Neuroscience, Maastricht University, Maastricht, The Netherlands 2: University Psychiatric Center Catholic University Leuven, Leuvensesteenweg, Kortenberg, Belgium

Publication date: August 1, 2007

mksg/acp/2007/00000116/00000002/art00006
dcterms_title,dcterms_description,pub_keyword
6
5
20
40
5

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more