@article {Wals:January 2006:0001-690X:23,
	author = "Wals, M.",
	author = "Reichart, C. G.",
	author = "Hillegers, M. H. J.",
	author = "Nolen, W. A.",
	author = "Van Os, J.",
	author = "Ormel, J.",
	author = "Verhulst, F. C.",
	title = "Prediction of change in level of problem behavior among children of bipolar parents",
	journal = "Acta Psychiatrica Scandinavica",
	volume = "113",
	year = "January 2006",
	abstract = "Wals M, Reichart CG, Hillegers MHJ, Nolen WA, Van Os J, Ormel J, Verhulst FC. Prediction of change in level of problem behavior among children of bipolar parents. &#60;br /&#62;Acta Psychiatr Scand 2005: 1&#8211;8. &#169; 2005 Blackwell Munksgaard. Objective:&#8194; <P></P>To determine the effects of familial loading, birth weight, and family problems on change in parent-reported problems across a 14-month period among children of bipolar parents. Method:&#8194; <P></P>Emotional and behavioral problems in a sample of 140 offspring of bipolar parents and familial loading in first- and second-degree relatives were assessed at two measurements. Parents reported the birth weight of their offspring and completed a questionnaire on family problems. Multiple linear regression analyses were performed to assess associations of the three predictors with change in problem scores at follow-up. Results:&#8194; <P></P>Familial loading of unipolar disorder was a unique predictor for an increase in problem scores from the first to the second measurement with <I>&#946;</I>-coefficients ranging from 0.17 to 0.25. Birth weight and family problems were not associated with change in problem scores across the two measurements. Conclusion:&#8194; <P></P>Familial loading of unipolar disorder predicted an increase in behavioral and emotional problems across the 14-month follow-up.",
	pages = "23-30(8)",
	url = "http://www.ingentaconnect.com/content/mksg/acp/2006/00000113/00000001/art00004"
	doi = "doi:10.1111/j.1600-0447.2005.00655.x"
}