Skip to main content

Atypical neuroleptic malignant syndrome caused by olanzapine

Buy Article:

$48.00 plus tax (Refund Policy)


Nielsen J, Bruhn AM. Atypical neuroleptic malignant syndrome caused by olanzapine.

Acta Psychiatr Scand 2005: 1–3. © 2005 Blackwell Munksgaard. Objective: 

Neuroleptic malignant syndrome (NMS) is a rare syndrome with four main symptoms: rigidity, hyperthermia, altered mental status and autonomic instability. We report a patient with an atypical manifestation of NMS. Method: 

A single case was reported. Results: 

A patient with pneumonia developed delirium and was treated with olanzapine and developed a NMS with fluctuating hyperthermia and autonomic instability during a month. Only slight rigidity was present. Creatine kinase was not elevated. The patient was severely agitated and manic. After discontinuation of olanzapine the patient showed no psychopathology or hyperthermia. Conclusion: 

NMS should be considered when patients treated with antipsychotics develop one or more symptoms of NMS.

Keywords: NMS; neuroleptic malignant syndrome; olanzapine

Document Type: Research Article


Affiliations: Unit for Psychiatric Research, Aalborg Psychiatric Hospital, Aalborg

Publication date: September 1, 2005


Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more