IngentaConnect Determinants of quality of life in first-episode psychosis

Authors: Malla A.K.; Norman R.M.G.¹; McLean T.S.²; MacDonald C.³; McIntosh E.³; Dean-Lashley F.³; Lynch J.³; Scholten D.; Ahmed R.⁴

Source: Acta Psychiatrica Scandinavica, Volume 109, Number 1, January 2004 , pp. 46-54(9)

Publisher: Blackwell Publishing

Abstract:

Malla AK, Norman RMG, McLean TS, MacDonald C, McIntosh E, Dean-Lashley F, Lynch J, Scholten D, Ahmed R. Determinants of quality of life in first-episode psychosis.

Acta Psychiatr Scand 2004: 109: 46–54. © Blackwell Munksgaard 2004. Objective:

To assess patient and/or illness characteristics associated with aspects of quality of life (QOL) in first-episode psychosis (FEP). Method:

Patient characteristics, symptom ratings and Wisconsin QOL scale (client version) were assessed. Data were analysed with correlation coefficients and a hierarchical regression analysis. Results:

Patients presented with varying levels of QOL on different domains. The level of ‘general satisfaction’ was related to age of onset and social premorbid adjustment; ‘weighted index of QOL’ to social premorbid adjustment and inversely to educational premorbid adjustment; ‘social relations’ inversely to duration of untreated psychosis (DUP), length of prodrome and negative symptoms; ‘psychological well-being’ inversely to depression and educational premorbid adjustment; ‘activities of daily living’ to social premorbid adjustment and inversely to negative symptoms; and ‘outlook on symptoms’ to level of depression. Conclusion:

Domains of self-rated QOL in FEP patients are differentially associated with malleable and non-malleable aspects of patient and illness characteristics.

Keywords: first-episode psychosis; quality of life

Document Type: Research article

DOI: 10.1046/j.0001-690X.2003.00221.x

Affiliations: 1: University of Western Ontario, Ontario, Canada 2: Prevention and Early Intervention Program for Psychosis, Douglas Hospital, Montreal, Canada 3: Prevention and Early Intervention Program for Psychosis, London, Ontario, Canada 4: University of Waterloo, Waterloo, Canada

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