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Schizophrenia and weight management: a systematic review of interventions to control weight

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Faulkner G, Soundy AA, Lloyd K. Schizophrenia and weight management: a systematic review of interventions to control weight.

Acta Psychiatr Scand 2003: 108: 324–332. © Blackwell Munksgaard 2003. Objective:

Weight gain is a frequent side effect of antipsychotic medication which has serious implications for a patient's health and well being. This study systematically reviews the literature on the effectiveness of interventions designed to control weight gain in schizophrenia. Method:

A systematic search strategy was conducted of major databases in addition to citation searches. Study quality was rated. Results:

Sixteen studies met the inclusion criteria. Five of eight pharmacological intervention studies reported small reductions in weight (<5% baseline body weight). All behavioural (including diet and/or exercise) interventions reported small reductions in, or maintenance of, weight. Conclusion:

Weight loss may be difficult but it is not impossible. Given the inconsistent results, the widespread use of pharmacological interventions cannot be recommended. Both dietary and exercise counselling set within a behavioural modification programme is necessary for sustained weight control.
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Keywords: review; schizophrenia; weight loss

Document Type: Review Article

Affiliations: 1: Faculty of Physical Education and Health, University of Toronto, Toronto, Ontario, Canada 2: Department of Exercise and Sport Science, School of Sport and Health Sciences, University of Exeter, Exeter, UK 3: Peninsula Medical School, Mental Health Research, Exeter, UK

Publication date: 01 November 2003

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