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Does co-morbid personality disorder increase the risk of suicidal behaviour in psychosis?

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Moran P, Walsh E, Tyrer P, Burns T, Creed F, Fahy T. Does co-morbid personality disorder increase the risk of suicidal behaviour in psychosis? Acta Psychiatr Scand 2003: 107: 441–448. © Blackwell Munksgaard 2003. Objective:

To examine the association between co-morbid personality disorder (PD) and suicidal behaviour over a 2-year period in a sample of patients with psychosis. Method:

A total of 670 patients with established psychotic illness were interviewed using a battery of instruments including a screen for co-morbid PD. The prevalence of attempted and completed suicide was measured over the next 2 years using multiple data sources. Logistic regression was used to examine whether those with co-morbid PD were at greater risk of suicidal behaviour compared with others. Results:

One hundred and eighty six patients (28%) were rated as having a co-morbid PD. After adjusting for all covariates, patients with co-morbid PD were significantly more likely to attempt or complete suicide over the 2-year period (adjusted odds ratio: 1.87; 95% CI: 1.02–3.42). Conclusion:

Co-morbid PD is independently associated with an increased risk of suicidal behaviour in psychosis. Early assessment of personality status should be part of the routine assessment of all psychiatric patients.
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Keywords: attempted suicide; co-morbidity; personality disorders; psychosis; suicide

Document Type: Research Article

Affiliations: 1: Health Services Research Department, 2: Department of Psychiatry and 3: Head of Public Health Medicine, Imperial College, London; 4: Head, Department of Psychiatry, St George's Hospital Medical School, London; 5: Professor of Psychological Medicine, School of Psychiatry and Behavioural Science, Manchester Royal Infirmary, Manchester, UK 6: Head, Section of Forensic Mental Health, Department of Psychiatry, Institute of Psychiatry, London;

Publication date: 2003-06-01

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