Skip to main content

Effect of pulsed radiofrequency for postherpetic neuralgia

Buy Article:

$43.00 plus tax (Refund Policy)

Background:

Postherpetic neuralgia (PHN) is one of the most intractable pain disorders, particularly among elderly patients. Lesioning of dorsal root ganglion (DRG) using pulsed radiofrequency (PRF) has shown pain reduction for PHN. We assessed the efficacy of PRF lesioning of DRG for PHN via an open, nonrandomized study. Methods:

Forty-nine patients with PHN refractory to conservative therapy were involved. After impedance and sensory electrical nerve stimulation thresholds were assessed, PRF was performed three times adjacent to the DRG of corresponding levels at 42 °C for 120 s under the fluoroscopic guidance. Pain ratings were conducted on a visual analogue scale at 4-, 8- and 12-week follow-up. The data were analyzed using the one-way ANOVA test. P<0.05 was considered to be statistically significant. Results:

There was excellent pain relief (about 55%) at 4 weeks after PRF lesioning adjacent to the DRG and the effectiveness was maintained at the subsequent 12-week follow-up. The pain duration, age and stimulation level did not influence the outcome. There were no procedure-related complications. Conclusions:

PRF lesioning of DRG showed significant pain relief compared with the conventional treatments in patients with intractable PHN. In order to elucidate the mode of action of PRF, further research is needed and the optimal electrical parameters of PRF have to be determined.
No References
No Citations
No Supplementary Data
No Article Media
No Metrics

Document Type: Research Article

Affiliations: 1: Seoul National University Bundang Hospital, Seoul, Korea, 2: Seoul National University Hospital, Seoul, Korea, 3: Seoul Muncipal Boramae Hospital, Seoul, Korea and 4: Korea University Hospital, Seoul, Korea

Publication date: 2008-09-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more