Risk factors for failure to extend labor epidural analgesia to epidural anesthesia for Cesarean section

$48.00 plus tax (Refund Policy)

Download / Buy Article:

Abstract:

Aim:: 

To identify parturients at risk of inability to extend labor epidural analgesia in whom alternative methods of anesthesia should be considered for Cesarean section (CS). Methods:: 

For 6 months, we prospectively studied women undergoing CS with a functioning epidural catheter in place from the delivery ward. All parturients received the same epidural protocol: bolus of bupivacaine 0.1% and fentanyl, followed by bupivacaine 0.1% and fentanyl (2 g/ml) 10–15 ml/h and an additional 5 ml of bupivacaine 0.125% as top-up according to patient request. Sixteen milliliters of lidocaine 2%, 1 ml of bicarbonate and 100 g of fentanyl were given for CS. Failed epidural analgesia was defined as the need to convert to general anesthesia. Results:: 

Of the 101 parturients studied, 20 (19.8%) required conversion to general anesthesia. In univariate analysis, the likelihood of failed epidural anesthesia was inversely correlated with parturient age (P = 0.014) and directly correlated with pre-pregnancy weight (P = 0.019), weight at the end of pregnancy (P = 0.003), body mass index at the end of pregnancy (P = 0.0004), gestational week (P = 0.008), number of top-ups (P = 0.0004) and visual analog scale (VAS) score 2 h before CS (P = 0.03). In multivariate analysis, the number of top-ups in the delivery ward was the best predictor of epidural anesthesia failure (odds ratio, 4.39; P = 0.005). Conclusion: 

Younger, more obese parturients at a higher gestational week, requiring more top-ups during labor and having a higher VAS score in the 2 h before CS are at risk for inability to extend labor epidural analgesia to epidural anesthesia for CS.

Keywords: Cesarean section; epidural analgesia; epidural anesthesia; general anesthesia; labor

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1399-6576.2006.01083.x

Affiliations: 1: Anesthesiology 2: Gynecology and Obstetrics 3: Epidemiology, Rabin Medical Center/Beilinson Campus, Petach-Tiqva and Sackler School for Medicine, Tel Aviv University, Tel Aviv, Israel

Publication date: August 1, 2006

Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more