Skip to main content

Rocuronium attenuates oculocardiac reflex during squint surgery in children anesthetized with halothane and nitrous oxide

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

Background: 

The oculocardiac reflex (OCR) may be activated during squint surgery. The aim of this study was to test whether rocuronium 0.4 mg kg−1 could reduce the frequency of OCR, and also whether a single dose of succinylcholine 1 mg kg−1 could affect the frequency of OCR during anesthesia with halothane in a nitrous oxide/oxygen mixture. Methods: 

A total of 161 ASA I children, 3–10 years old, undergoing elective surgery of the medial rectus muscle (MRM) were randomly assigned to three groups. Group R (n = 51), received 0.4 mg kg−1 of rocuronium intravenously before endotracheal intubation. Group S (n = 58) received 1 mg kg−1 of succinylcholine. Group C (controls, n = 52) received no relaxant. Oculocardiac reflex was defined as a reduction in heart rate (HR) >= 15% and/or the appearance of any other arrhythmias, during manipulation of the MRM. Analysis of variance (anova), chi-squared, Kruskal–Wallis, and Student's t-tests were used for statistical analysis; P< 0.05 was considered statistically significant. Results: 

In group R, OCR occurred in 15/51 (29%) of children, in group S in 31/58 (53%), and in group C in 23/52 (44%) (χ2 = 6.46, P = 0.049). In group R, the incidence of arrhythmias such as nodal rhythms, supraventricular and ventricular premature beats was 6%, compared with 22% in group S and 19% in group C (χ2 = 6.01, P = 0.040). However, there was no reduction in the occurrence of bradycardia (χ2 = 0.16, P = 0.924)., Conclusion: 

Rocuronium reduced the frequency of OCR, mainly by reducing the incidence of supraventricular and ventricular premature beats.

Keywords: Halothane; inhalational anesthesia; muscle relaxants; oculocardiac reflex; pediatric anesthesia; rocuronium; squint surgery; strabismus; succinylcholine

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1399-6576.2004.00523.x

Affiliations: 1: Department of Anesthesiology and Intensive Care, University Hospital Split, and 2: Department of Neuroscience, University of Split Medical School, Split, Croatia

Publication date: November 1, 2004

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Partial Open Access Content
Partial Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more