Skip to main content

Between Scylla and Charybdis: A bleomycin-exposed patient with Cohen syndrome

Buy Article:

$51.00 plus tax (Refund Policy)


Chemotherapy with bleomycin may cause a syndrome of pulmonary sensitivity to supranormal inspired oxygen concentrations that persists for an unknown period of time after exposure. We present a mentally retarded adolescent patient in whom supranormal inspired oxygen was temporarily necessary to manage her difficult airway. Subsequently her pulmonary function deteriorated acutely and, after intermittent stabilization, irreversibly. In this case, bleomycin exposure may have played a pivotal role in modulating minor insults to trigger fatal acute respiratory distress syndrome (ARDS).

Keywords: Aspiration; Cohen syndrome; bleomycin; difficult airway; oxygen toxicity

Document Type: Research Article


Affiliations: 1: Department of Anesthesiology, Rabin Medical Center, Beilinson Campus, Petach Tikvah, Israel, 2: Department of Oral Medicine, Hadassah Medical Center, The Hebrew University School of Medicine, Jerusalem, Israel, 3: Department of Anesthesiology and Critical Care Medicine, and 4: Department of Anesthesiology, University of Wisconsin Medical School, Madison, Wisconsin

Publication date: 2003-09-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more