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Sevoflurane: an ideal agent for adult day-case anesthesia?

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Sevoflurane has several properties which make it potentially useful as a day case anaesthetic. Following induction of anaesthesia with propofol, awakening from sevoflurane is faster compared to isoflurane, faster or similar compared to propofol and comparable (in the majority of studies) to desflurane. Subsequent recovery and discharge is generally similar following all agents. Sevoflurane may also be used to induce anaesthesia, which is generally well-received and causes less hypotension and apnoea compared to propofol.

When used as a maintenance anaesthetic, the incidence of postoperative nausea and vomiting after sevoflurane is comparable to other inhaled anaesthetics, but this complication appears more common after inhaled inductions. The tolerability and low solubility of sevoflurane facilitate titration of anaesthesia and may reduce the need for opioid analgesia, which in turn may limit the occurrence of nausea and vomiting.

Keywords: Anaesthetics, inhaled; Anaesthetics, intravenous; Complications, postoperative nausea and vomiting; Day case anaesthesia; propofol; sevoflurane, isoflurane, desflurane

Document Type: Review Article


Affiliations: Department of Anaesthesia, Keele University/University Hospital of North Staffordshire, Stoke-on-Trent, Staffordshire, UK

Publication date: September 1, 2003


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