A randomised double-blind evaluation of adenosine as adjunct to sufentanil in spinal labour analgesia

$48.00 plus tax (Refund Policy)

Download / Buy Article:



Intrathecal injection of sufentanil offers labour pain relief of short duration. This double-blind randomised study evaluates if the combination of adenosine to sufentanil could give relevant prolongation (40%) of the duration of sufentanil spinal analgesia. Methods:

Twenty-five healthy parturients requesting labour analgesia were included. Patients received 10 µg of sufentanil + 500 µg of adenosine or 10 µg of sufentanil intrathecally. Pain intensity and duration of pain relief were assessed. Results:

Pain relief was equal between groups. Duration of analgesia was not increased by adenosine + sufentanil, 99 ± 54 min, vs. sufentanil, 89 ± 56 min. Conclusion:

Adding 500 µg of adenosine to 10 µg of sufentanil could not provide any prolongation of labour pain relief.

Keywords: Adenosine; intrathecal; labour analgesia; opioids; spinal analgesia

Document Type: Research Article

DOI: http://dx.doi.org/10.1034/j.1399-6576.2003.00110.x

Affiliations: 1: Department of Anaesthesia and Intensive Care, Danderyd Hospital, Danderyd and 2: Department of Anaesthesia and Intensive Care, Huddinge University Hospital, Stockholm, Sweden

Publication date: May 1, 2003

Related content



Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more