Skip to main content

Hemodynamic and oxygenation profiles in the early period after hyperbaric oxygen therapy: an observational study of intensive-care patients

Buy Article:

$43.00 plus tax (Refund Policy)

Background:

We studied whether hemodynamic and oxygenation profiles are altered in critically ill patients after exposure to hyperbaric oxygen (HBO). Methods:

Ten intensive-care patients (two females, eight males) undergoing HBO treatment after major abdominal surgery, after burn injury and after CO poisoning were included. All subjects were put on mechanical ventilation and received continuous sedation, and had HBO treatment at 2.2 absolute atmospheres for 50 min. Design:

Observational prospective study, and repeated measure design. Results:

Hemodynamic and oxygen transport patterns were determined before (C0), 1 h (C1) and 2 h (C2) after HBO therapy with continuous cardiac output dual oximetry pulmonary arterial catheter, a central venous and radial arterial line. Data were analyzed with non-parametric repeated measure analysis. Key results are expressed as a percentage of baseline (C0 values correspond to 100%) at C1 and C2 (median values, lower and upper limit of confidence interval): cardiac index [C1: 105% (98–135), C2: 99% (91–117), P = 0.19], systemic (P = 0.62) and pulmonary vascular (P = 0.76) resistance indices were unchanged, but pulmonary venous admixture (Qs/Qt) increased [C1: 173% (112–298), C2: 140% (92–241), P = 0.00002)] and arterial oxygen tension decreased [C1: 76% (67–94), C2: 82% (72–112), P = 0.010]. Conclusion:

The hemodynamic profile remained unaffected. The increase in Qs/Qt and the decrease in PaO2 may be attributed to the inhalation of HBO, and both are reversible.
No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Keywords: Critically ill; hemodynamics; hyperbaric oxygen; oxygen transport; pulmonary venous admixture

Document Type: Research Article

Affiliations: 1: Department of Anesthesiology and Critical Care Medicine, 2: Medical Statistics, University Medical School of Graz, Graz, Austria 3: Thoracic and Hyperbaric Surgery and

Publication date: 2003-05-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more