Skip to main content

Auditory evoked potential monitoring with the AAITM-index during spinal surgery: decreased desflurane consumption

Buy Article:

$51.00 plus tax (Refund Policy)


The auditory evoked potential (AEP) is sensitive to the depth of anesthesia. The A-line monitor is a novel device that processes the amplitude and latency of the AEP during the mid-latency time window to provide a simple numerical index, the AAI™-index. The hypothesis of the present study was that titration of anesthetic depth (desflurane) by means of the AAI™-index could decrease the consumption of the main anesthetic and shorten emergence times. Methods:

Thirty ASA I–II patients scheduled for elective open spine surgery under general anesthesia were randomly allocated to two groups. Group I (n=15), the main anesthetic, desflurane, was titrated with a target AAI™-index of 20±5. Group II (n=15), desflurane was titrated according to routine clinical signs, including heart rate, blood pressure, sweating and tears. No fixed MAC-multiple was sought. The primary study variable was desflurane consumption; and secondary study variables were time to extubation and orientation. Results:

All patients had an uncomplicated course and no patients showed signs of awareness or had any recall postoperatively. AAI™-index guidance reduced desflurane consumption by 29% and improved emergence. Time until extubation and orientation and ability to state name and date of birth was significantly shortened among AAI™-index titrated patients. Conclusion:

Titrating depth of desflurane anesthesia using AAI™-index guidance decreased main anesthetic consumption and improved emergence during spine surgery.
No References
No Citations
No Supplementary Data
No Data/Media
No Metrics

Keywords: AAI™-index; a-line index; auditory evoked potentials; desflurane; general anesthesia

Document Type: Research Article

Affiliations: 1: Orthopaedics and 2: Department of Cardiothoracic Anesthetics and Intensive Care, Karolinska Hospital, Stockholm, Sweden 3: Anesthesia, Sabbatsberg Hospital, and

Publication date: 2002-08-01

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more