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Open Access Practice-Based Knowledge Discovery for Comparative Effectiveness Research: An Organizing Framework La découverte de connaissances fondée sur la pratique à des fins de recherche sur l'efficacité comparative : un cadre organisationnel

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Abstract:

Electronic health information systems can increase the ability of health-care organizations to investigate the effects of clinical interventions. The authors present an organizing framework that integrates outcomes and informatics research paradigms to guide knowledge discovery in electronic clinical databases. They illustrate its application using the example of hospital acquired pressure ulcers (HAPU). The Knowledge Discovery through Informatics for Comparative Effectiveness Research (KDI-CER) framework was conceived as a heuristic to conceptualize study designs and address potential methodological limitations imposed by using a single research perspective. Advances in informatics research can play a complementary role in advancing the field of outcomes research including CER. The KDI-CER framework can be used to facilitate knowledge discovery from routinely collected electronic clinical data.

French
Les systèmes d'information électroniques sur la santé peuvent accroître la capacité des organismes de soins de santé à étudier les effets des interventions cliniques. Le présent article propose un cadre organisationnel qui intègre les paradigmes de la recherche en informatique et de la recherche sur les résultats afin de faciliter la création de connaissances à l'aide de bases de données cliniques. Afin d'illustrer le cadre proposé, les auteurs l'appliquent à l'exemple des plaies de pression. Ce cadre de création de connaissances à l'aide de l'informatique aux fins de la recherche comparative sur l'efficacité des traitements (CCI-RCET) a été conçu dans le but de servir d'outil heuristique pour la conceptualisation des modèles d'étude et de surmonter les contraintes méthodologiques que peut éventuellement imposer toute perspective de recherche unique. Les percées de la recherche en informatique appliquée peuvent jouer un rôle complémentaire dans le développement du champ de la recherche sur les résultats, y compris de la recherche comparative sur l'efficacité des traitements. Le cadre de CCI-RCET peut être utilisé afin de favoriser la production de connaissances à partir des données cliniques électroniques qui sont recueillies de façon systématique.

Keywords: COMPARATIVE EFFECTIVENESS; DATA MINING; HEALTH SERVICES; INFORMATICS; KNOWLEDGE GENERATION; RESEARCH

Document Type: Short Communication

Publication date: March 1, 2013

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