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Drug interactions and dual diagnosis

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Purpose ‐ Adverse drug reactions (ADR) and interactions for patients who use substances and have a mental health problem is an area that lacks attention in research, practice and policy. The purpose of this paper is to examine what is currently known about this topic. Design/methodology/approach ‐ The paper explores the available literature and specialist information available on this subject. Findings ‐ This is a complex area, which is compounded by limited empirical evidence. However, information is available which when combined with individual patient assessment there is the potential to reduce the risk of detrimental ADR and improve concordance to medication. Originality/value ‐ The paper offers pragmatic suggestions which aim to improve the knowledge of practitioners and lessen the potential harm to patients.

Keywords: Adverse drug reaction; Drug interaction; Pharmacodynamics; Pharmacokinetics

Document Type: Research Article


Publication date: August 9, 2013

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