IngentaConnect Evaluation of the combination of amoxicillin trihydrate, diclofen...

Authors: Evcil, Mehmet Sinan; Keleş, Ali; Uzun, İsmail

Source: The Pain Clinic, Volume 18, Number 2, 2006 , pp. 181-185(5)

Abstract:

Aims: The purpose of this study is to evaluate the efficacy of drug combination on the flare up that may occur after pulpectomy in patients treated for painful irreversible pulpitis.

Material and methods: Thirty emergency patients were included in the study. All the patients who participated in the study suffered from irreversible pulpitis with spontaneous moderate-to-severe pain. The patients were randomly divided into two groups of 15 patients, all of whom were subjected to endodontic treatment. They were randomly classified as Group A, to whom medicine combination was administered, and Group B to whom medicines were not administered. The ingredients of the combination were 50 mg of diclofenac potassium, 500 mg of amoxicillin trihydrate and 250 mg ornidazol. Pain in the groups was statistically compared according to Mann–Whitney and Wilcoxon Signed Ranks test before and after the endodontic treatment.

Results: The general evaluation of the pain in patients subjected to the administration of the medicine combination showed a significant difference (p < 0.05) in the relief of pain in the first 6 h and at the end of the first week as compared with those to whom nothing was administered. It can be concluded from the results that this medicine combination can be helpful in the control of pain due to endodontic treatment.

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Evaluation of the combination of amoxicillin trihydrate, diclofenac potassium and ornidazol for the management of endodontic pain