Glow discharge modified tissue culture polystyrene: role of surface chemistry in cellular attachment and proliferation
Authors: Mitchell, S. A.; Davidson, M. R.; Bradley, R. H.
Source: Surface Engineering, Volume 22, Number 5, October 2006 , pp. 337-344(8)
Publisher: Maney Publishing
Abstract:A radio frequency glow discharge has been used to selectively deposit non-polar hydrocarbon films onto tissue culture grade polystyrene surfaces. The resulting surfaces have been studied using X-ray photoelectron spectroscopy, contact angle analysis and atomic force microscopy. Regions with differing surface chemistry and polarity have been produced on the same substrate using a simple masking technique and allowed the spatially controlled attachment of mammalian cells. The attachment of cells to plasma modified tissue culture polystyrene surfaces has been correlated to the concentration of specific oxygen functional groups.
Document Type: Research Article
Publication date: 2006-10-01
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