Changes of markers of oxidative stress during menstrual cycle

Authors: Karowicz-Bilinska, Agata1; Plodzidym, Magdalena2; Krol, Joanna2; Lewinska, Anna2; Bartosz, Grzegorz3

Source: Redox Report, Volume 13, Number 5, October 2008 , pp. 237-240(4)

Publisher: Maney Publishing

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Abstract:

The levels of urinary hydrogen peroxide and thiobarbituric acid reactive substances have been compared during the menstrual cycle of 12 regularly menstruating women. Higher level of both indices of oxidative stress (normalized with respect to creatinine content) were found in the luteal phase of the cycle. These results give further evidence for the usefulness of urinary hydrogen peroxide and thiobarbituric acid reactive substances as potential biomarkers of oxidative stress and for the antioxidant action of estrogens.

Keywords: HYDROGEN PEROXIDE; LIPID PEROXIDATION; ESTROGEN; OXIDATIVES STRESS; MENSTURUAL CYCLE; URINE

Document Type: Research Article

DOI: http://dx.doi.org/10.1179/135100008X308993

Affiliations: 1: High-Risk Pregnancy Unit, Medical University of Łodz, Łodz, Poland 2: Department of Biochemistry and Cell Biology, University of Rzeszow, Rzeszow, Poland 3: Department of Biochemistry and Cell Biology, University of Rzeszow, Rzeszow, Poland; Department of Molecular Biophysics, University of Łodz, Łodz, Poland

Publication date: 2008-10-01

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