Home >> Redox Report, Volume 7, Number 5

Paraoxonase and other coronary risk factors in a community-based cohort

Authors: Cohen, Jacob1; Jenkins, Alicia2; Karschimkus, Connie2; Qing, Su3; Lee, Chee Teik2; O'Dea, Kerin4; Best, James2; Rowley, Kevin2

Source: Redox Report, Volume 7, Number 5, October 2002 , pp. 304-307(4)

Publisher: Maney Publishing

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Abstract:

Oxidative damage to circulating lipids and vascular tissues contributes to the initiation and progression of atherosclerosis. High density lipoprotein provides protection from atherosclerosis and the enzyme paraoxonase may contribute to this effect. The aim of the present study was to examine the trends in paraoxonase activity during the course of a community-directed life-style intervention, and relationships of paraoxonase activity to other coronary heart disease risk factors, in a cohort of Australian Aboriginal people.

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Document Type: Regular Paper

DOI: http://dx.doi.org/10.1179/135100002125000848

Affiliations: 1: Department of Medicine, University of Melbourne, Fitzroy, Victoria, Australia; School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA 2: Department of Medicine, University of Melbourne, Fitzroy, Victoria, Australia 3: Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia 4: Menzies School of Health Research, Casuarina, Northern Territory, Australia

Publication date: 2002-10-01

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