Antioxidant properties of a Tinospora cordifolia polysaccharide against iron-mediated lipid damage and γ-ray induced protein damage
Authors: Subramanian, Mahesh; Chintalwar, Gajanan J.; Chattopadhyay, Subrata
Source: Redox Report, Volume 7, Number 3, June 2002 , pp. 137-143(7)
Publisher: Maney Publishing
Abstract:The antioxidant activity of an arabinogalactan polysaccharide (TSP) isolated from Tinospora cordifolia, an Indian medicinal plant, was studied. The polysaccharide showed good protection against iron-mediated lipid peroxidation of rat brain homogenate as revealed by the thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxide (LOOH) assays. TSP also provided significant protection to protein against ?-ray induced damage. The protective action can possibly be explained by its very high reactivity towards DPPH, superoxide radicals and the most damaging of radicals, the hydroxyl radical.
Document Type: Research Article
Affiliations: Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India
Publication date: 2002-06-01