Authors: Subramanian, Mahesh; Chintalwar, Gajanan J.; Chattopadhyay, Subrata

Source: Redox Report, Volume 7, Number 3, June 2002 , pp. 137-143(7)

Publisher: Maney Publishing

Abstract:

The antioxidant activity of an arabinogalactan polysaccharide (TSP) isolated from Tinospora cordifolia, an Indian medicinal plant, was studied. The polysaccharide showed good protection against iron-mediated lipid peroxidation of rat brain homogenate as revealed by the thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxide (LOOH) assays. TSP also provided significant protection to protein against ?-ray induced damage. The protective action can possibly be explained by its very high reactivity towards DPPH, superoxide radicals and the most damaging of radicals, the hydroxyl radical.

Keywords:

Document Type: Research Article

DOI: http://dx.doi.org/10.1179/135100002125000370

Affiliations: Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India

Publication date: 2002-06-01

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