Advances in thrombolytics and mechanical devices for treatment of acute ischemic stroke
Authors: Alkawi, Ammar1; Kirmani, Jawad F.1; Janjua, Nazli1; Khatri, Ismail1; Ahmed, Shafiuddin1; Divani, Afshin A.1; Qureshi, Adnan I.1
Source: Neurological Research, Volume 27, Supplement 1, October 2005 , pp. 42-49(8)
Publisher: Maney Publishing
- Free Content
- New Content
- Subscribed Content
- Free Trial Content
Abstract:
Stroke is a leading cause of death and disability. Recently, there have been advances in the treatment of acute ischemic stroke aimed at re-establishing blood flow to the affected area in an effort to save the ischemic penumbra surrounding the area of infarction. This is achieved by the use of thrombolytics intravenously or intra-arterially. The use of mechanical devices facilitates the function of pharmacological agents used in addition to minimizing the associated risks. In this review, we first discuss the therapeutic potentials and strategies employed in using different thrombolytics in management of acute ischemic stroke. Subsequently, we discuss the recent advances and therapeutic applications of mechanical devices in this field.Keywords: STROKE; THROMBOLYTICS; MECHANICAL DEVICES; RECANALIZATION; STENTS
Document Type: Research article
DOI: 10.1179/016164105X25306
Affiliations: 1: Zeenat Qureshi Stroke Research Center, Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA
- Free Content
- New Content
- Subscribed Content
- Free Trial Content
Click here for Page Help