Cerebral perfusion and blood flow in neurotrauma

Authors: Zwienenberg, Marike; Muizelaar, J. Paul

Source: Neurological Research, Volume 23, Numbers 2-3, March 2001 , pp. 167-174(8)

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Abstract:

Post-traumatic cerebral ischemia is associated with a poor prognosis. Optimization of cerebral perfusion and blood flow thus plays a key role in contemporary head injury management. However, understanding of the pathophysiology of severe head injury is required for optimal patient management. This article explains the relationships between cerebral blood flow and metabolism and summarizes the current understanding of how these parameters can be helpful in the treatment of patients with severe head injuries. [Neurol Res 2001; 23: 167-174]

Keywords: CO2-REACTIVITY; AUTOREGULATION; CEREBRAL BLOOD VOLUME; CEREBRAL METABOLISM; CEREBRAL BLOOD FLOW; ISCHEMIA

Document Type: Research Article

DOI: http://dx.doi.org/10.1179/016164101101198505

Affiliations: Department of Neurological Surgery, University of California Davis, Sacramento, CA, USA

Publication date: 2001-03-01

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