Lack of association between MTHFR C677T and MTHFR A1298C genetic polymorphisms and mental retardation

Authors: Saccucci, Patrizia¹; Compagnone, Eliana²; Verrotti, Alberto³; Galasso, Cinzia²; Curatolo, Paolo²

Source: Nutritional Neuroscience, Volume 11, Number 5, October 2008 , pp. 241-242(2)

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Abstract:

Findings suggest that there is no association between MTHFR C677T and MTHFR A1298C and mental retardation in the studied Italian population and that these polymorphisms are not contributing to the aetiology of mental retardation.

Keywords: MTHFR A1298C; POLYMORPHISM; MENTAL RETARDATION; MTHFR C677T

Document Type: Short Communication

DOI: http://dx.doi.org/10.1179/147683008X301595

Affiliations: 1: Division of Human Population and Environmental Pathology, Department of Biopathology and Imaging Diagnostics, University of Rome 'Tor Vergata', Rome, Italy 2: Department of Neurosciences, Pediatric Neurology Unit, University of Rome 'Tor Vergata', School of Medicine, Rome, Italy 3: Department of Pediatrics, University of Chieti, Gabriele D'Annunzio, Chieti, Italy

Publication date: 2008-10-01

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