The Langerhans Cell: Sentinel of the Body's Immune Defense System. I. Morphology and Microscopic Methods of Detection
Author: Elias, Jules M.
Source: Journal of Histotechnology, Number 2, June 1987 , pp. 121-124(4)
Publisher: Maney Publishing
Abstract:The Langerhans cell (LC), although found in the skin, is one of the cells of the lymphoid system; it is believed to originate in the bone marrow. The LC wanders to other parts of the body, where it plays an important part in the immune response by helping to present antigen to T lymphocytes. Langerhans cells are differentiated from macrophages, melanocytes, T lymphocytes, and interdigitating cells by a number of markers, the most useful being OKT-6/Leu6 and the Birbeck granule. (The J Histotechnol 10: 121, 1987).
Document Type: Research Article
Publication date: 1987-06-01
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