Multi-resistant viridans streptococcal pneumonia and sepsis in the ventilated newborn
Authors: Ayla Günlemez1; Begüm Atasay1; Haluk Güriz2; Derya Aysev2; Saadet Arsan1
Source: Annals of Tropical Paediatrics: International Child Health, Volume 24, Number 3, September 2004 , pp. 253-258(6)
Publisher: Maney Publishing
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Abstract:
Mechanical ventilation increases the frequency of nosocomial infections. This study describes the frequency of multi-resistant viridans streptococcal colonisation, the clinical course of nosocomial sepsis and ventilator-associated pneumonia in mechanically ventilated neonates in the neonatal intensive care unit of Ankara University Hospital. Seventy-nine ventilated newborns were enrolled. Broncho-alveolar lavage culture and blood cultures were positive in 44 (56%) and 17 (22%) patients, respectively. The most predominant micro-organisms in broncho-alveolar lavage cultures were multi-resistant viridans streptococci (29, 66%). Viridans streptococci were also one of the predominant organisms in blood cultures (5/17, 29%). In 29 patients with broncho-alveolar lavage positive for viridans streptococci, nine (31%) had colonisation, 15 (52%) had ventilator-associated pneumonia and five (17%) had sepsis owing to viridans streptococcus. Ventilator-associated pneumonia was encountered in 52/1000 ventilation days. Mortality was caused by infection in three (10%) of them. Mechanically ventilated neonates in our neonatal intensive care unit had a high rate of both multi-resistant viridans streptococcus airway colonisation and subsequent ventilator-associated pneumonia and sepsis.Document Type: Research article
DOI: 10.1179/027249304225018993
Affiliations: 1: Division of Neonatology, Ankara University School of Medicine, Ankara, Turkey 2: Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey
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