Authors: Günlemez, Ayla¹; Atasay, Begüm¹; Güriz, Haluk²; Aysev, Derya²; Arsan, Saadet¹

Source: Annals of Tropical Paediatrics: International Child Health, Volume 24, Number 3, September 2004 , pp. 253-258(6)

Publisher: Maney Publishing

Abstract:

Mechanical ventilation increases the frequency of nosocomial infections. This study describes the frequency of multi-resistant viridans streptococcal colonisation, the clinical course of nosocomial sepsis and ventilator-associated pneumonia in mechanically ventilated neonates in the neonatal intensive care unit of Ankara University Hospital. Seventy-nine ventilated newborns were enrolled. Broncho-alveolar lavage culture and blood cultures were positive in 44 (56%) and 17 (22%) patients, respectively. The most predominant micro-organisms in broncho-alveolar lavage cultures were multi-resistant viridans streptococci (29, 66%). Viridans streptococci were also one of the predominant organisms in blood cultures (5/17, 29%). In 29 patients with broncho-alveolar lavage positive for viridans streptococci, nine (31%) had colonisation, 15 (52%) had ventilator-associated pneumonia and five (17%) had sepsis owing to viridans streptococcus. Ventilator-associated pneumonia was encountered in 52/1000 ventilation days. Mortality was caused by infection in three (10%) of them. Mechanically ventilated neonates in our neonatal intensive care unit had a high rate of both multi-resistant viridans streptococcus airway colonisation and subsequent ventilator-associated pneumonia and sepsis.

Document Type: Research Article

DOI: http://dx.doi.org/10.1179/027249304225018993

Affiliations: 1: Division of Neonatology, Ankara University School of Medicine, Ankara, Turkey 2: Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey

Publication date: 2004-09-01

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• In 2012 Annals of Tropical Paediatrics changed its name to Paediatrics and International Child Health to reflect changes and developments in the subject area. View the issues of Paediatrics and International Child Health available online.
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