IngentaConnect A parasitological survey, in rural Zanzibar, of pre-school childr...

Authors: Sousa-Figueiredo, J.C.¹; Basáñez, M.G.²; Mgeni, A.F.³; Khamis, I.S.³; Rollinson, D.⁴; Stothard, J.R.⁴

Source: Annals of Tropical Medicine and Parasitology, Volume 102, Number 8, December 2008 , pp. 679-692(14)

Abstract:

'Kick-out-Kichocho' is an integrated helminth-control initiative that is aimed at reducing the burden of urinary schistosomiasis and soil-transmitted helminthiases (STH) on Zanzibar Island (Unguja), in Tanzania. Like other initiatives based on preventive chemotherapy, the programme is mainly school-based and, consequently, pre-school children (aged ≤6 years) are not targeted specifically. To assess the importance of urinary schistosomiasis, STH and malaria, as well as the occurrence of anaemia and growth retardation among these younger children, an epidemiological survey has been undertaken, in a rural area of Unguja, among 152 pre-school children and their 113 mothers. In the pre-school children investigated, urinary schistosomiasis was rare because of the children's lack of contact with environmental water. Malaria was also rare in the children, probably as a consequence of the study season, the widespread use of insecticide-treated bednets and the good access to first-line antimalarial drugs. In contrast, the prevalences of infection with at least one soil-transmitted helminth and of anaemia were alarmingly high among the pre-school children, at 50.0% [95% confidence interval (CI)=40.4%-59.6%) and 73.4% (CI=?65.2%-80.5%), respectively; the corresponding values in the children's mothers were 35.2% (CI=25.4%-45.9%) and 25.9% (CI=18.0%-35.3%). In the rural study area, Kandwi was identified as a hamlet with particularly high levels of transmission of soil-transmitted helminths, and household aggregations of STH were common. To reduce the present health inequities, the future integration of pre-school children within ongoing anthelmintic-control programmes in schools is strongly recommended.

Document Type: Research article

DOI: 10.1179/136485908X337607

Affiliations: 1: Department of Infectious Disease Epidemiology, Imperial College London (St Mary's Campus), Norfolk Place, London W2 1PG, U.K; Wolfson Wellcome Biomedical Laboratories, Biomedical Parasitology Division, Department of Zoology, Natural History Museu 2: Department of Infectious Disease Epidemiology, Imperial College London (St Mary's Campus), Norfolk Place, London W2 1PG, U.K 3: Helminth Control Laboratory Unguja, Helminth Control Programme, Zanzibar, Tanzania 4: Wolfson Wellcome Biomedical Laboratories, Biomedical Parasitology Division, Department of Zoology, Natural History Museum, Cromwell Road, London SW7 5BD, U.K

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A parasitological survey, in rural Zanzibar, of pre-school children and their mothers for urinary schistosomiasis, soil-transmitted helminthiases and malaria, with observations on the prevalence of anaemia