Authors: Suzuki, A.¹; Hamano, S.²; Shirakawa, T.³; Watanabe, K.⁴; Endo, T.⁵; Sharma, S.⁶; Jha, B.⁶; Acharya, G. P.⁶; Nishiyama, K.³; Fukumaki, Y.⁷; Kobayashi, S.⁸

Source: Annals of Tropical Medicine and Parasitology, Volume 101, Number 2, March 2007 , pp. 113-122(10)

Publisher: Maney Publishing

Abstract:

Among four ethnic groups in a lowland area of Nepal, the prevalences of abnormal haemoglobin, thalassaemia, glucose-6-phosphate-dehydrogenase (G6PD) deficiency, hereditary South–east Asian ovalocytosis (SAO) and Duffy blood-group antigen Fy/Fy were determined and related to each group's habitat. The group that has lived for many decades in a malaria-endemic lowland area, the Danuwar, was found to have a high prevalence of ?⁺-thalassaemia (79.4%) and low prevalences of haemoglobin E and G6PD deficiency. Much lower prevalences of ?⁺-thalassaemia were observed in the Newar (20.5%), Parbate (16.5%) and Tamang (8.8%), who, until the 1950s, all spent their hot-season nights in malaria-free areas at higher altitudes. No subjects with any other identified abnormal haemoglobin, ?-thalassaemia, SAO or Fy/Fy were detected.

Document Type: Research Article

DOI: http://dx.doi.org/10.1179/136485907X154539

Affiliations: 1: Department of Pediatrics, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, 565-0871, Japan 2: Department of Parasitology, Graduate School of Medicine, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan 3: Faculty of Health Sciences, School of Medicine, Kobe University, 7-10-2 Tomogaoka, Suma-ku, Kobe, 654-0142, Japan 4: Department of Parasitology, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, 852-8523, Japan 5: Kyushu Junior College of Kinki University, 1-5-30 Komodahigashi, Iizuka, 820-0016, Japan 6: Institute of Medicine, Tribhuvan University, P.O. Box 1524, Kathmandu, Nepal 7: Research Center for Genetic Information, Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan 8: Department of Geography, Graduate School of Letters, Osaka University, 1-5 Machikaneyama, Toyonaka, 560-8532, Japan

Publication date: 2007-03-01

More about this publication?

• In 2012 Annals of Tropical Medicine and Parasitology changed its name to Pathogens and Global Health to reflect changes and developments in the subject area. View the issues of Pathogens and Global Health available online..
• Editorial Board
• Information for Authors
• Submit a Paper
• Subscribe to this Title
• Information for Advertisers
• Terms & Conditions
• Top articles
• Health Sciences Spotlight
• Abstracted in
• ingentaconnect is not responsible for the content or availability of external websites

Related content

• In this: publication
• By this: publisher
• In this Subject: Internal Medicine
• By this author: Suzuki, A. ;  Hamano, S. ;  Shirakawa, T. ;  Watanabe, K. ;  Endo, T. ;  Sharma, S. ;  Jha, B. ;  Acharya, G. P. ;  Nishiyama, K. ;  Fukumaki, Y. ;  Kobayashi, S.

Website © Publishing Technology. Article copyright remains with the publisher, society or author(s) as specified within the article.

• Terms and conditions
• Privacy policy
• Information for advertisers