Authors: Escobedo, A. A.¹; Núñez, F. A.²; Moreira, I.²; Vega, E.³; Pareja, A.⁴; Almirall, P.⁵

Source: Annals of Tropical Medicine and Parasitology, Volume 97, Number 4, June 2003 , pp. 367-371(5)

Publisher: Maney Publishing

Abstract:

In a comparative trial, 165 Cuban children with confirmed giardiasis were randomized to receive albendazole (400 mg/day for 5 days), chloroquine (10 mg/kg twice daily for 5 days) or tinidazole (50 mg/kg, as a single dose). Parasitological follow-up was based on faecal samples collected 7 and 10 days after the completion of treatment. The tinidazole and chloroquine appeared equally effective (P > 0.05), curing 91% and 86% of the children treated, respectively, and significantly better (P < 0.01) than the albendazole, which only cured 62% of the children given it. All three drugs were well accepted and tolerated, with only mild, transient and self-limiting side-effects reported. Chloroquine appears to be a good alternative to tinidazole for the treatment of paediatric patients with giardiasis.

Keywords:

Document Type: Research Article

DOI: http://dx.doi.org/10.1179/000349803235002290

Affiliations: 1: Departamento de Parasitología, Hospital Pediatrico 'Pedro Borrás', Calle F No. 616 esquina a 27, Plaza Ciudad de La Habana, CP 10400, Cuba 2: Departamento de Parasitologia, Instituto 'Pedro Kourí', Autopista Novia del Mediodia, Km 6.5, La Lisa, Ciudad de La Habana, CP 11300, Cuba 3: Departamento de Parasitologia, Hospital Pediatrico 'Pedro Borrás', Calle F No. 616 esquina a 27, Plaza Ciudad de La Habana, CP 10400, Cuba 4: Departamento de Parasitologia, Facultad de Medicina, Universidad de San Martín de Porres, Alameda del Corregidor cdra 15 s/n, Lima 12, Peru 5: Hospital 'Carlos J. Finlay', Calle 31 y 114, Marianao, Ciudad de La Habana, Cuba

Publication date: 2003-06-01

More about this publication?

• In 2012 Annals of Tropical Medicine and Parasitology changed its name to Pathogens and Global Health to reflect changes and developments in the subject area. View the issues of Pathogens and Global Health available online..
• Editorial Board
• Information for Authors
• Submit a Paper
• Subscribe to this Title
• Information for Advertisers
• Terms & Conditions
• Top articles
• Health Sciences Spotlight
• Abstracted in
• ingentaconnect is not responsible for the content or availability of external websites

Related content

• In this: publication
• By this: publisher
• In this Subject: Internal Medicine
• By this author: Escobedo, A. A. ;  Núñez, F. A. ;  Moreira, I. ;  Vega, E. ;  Pareja, A. ;  Almirall, P.

Website © Publishing Technology. Article copyright remains with the publisher, society or author(s) as specified within the article.

• Terms and conditions
• Privacy policy
• Information for advertisers