Study of the Mechanism for Regulating ribR Gene Activity in Bacillus subtilis

Authors: Solovieva I.M.¹; Kreneva R.A.¹; Errais L.L.²; Mironov A.S.²; Perumov D.A.¹

Source: Russian Journal of Genetics, Volume 40, Number 5, May 2004 , pp. 580-583(4)

Publisher: MAIK Nauka/Interperiodica

Buy & download fulltext article:

Price: $45.00 plus tax (Refund Policy)

Abstract:

Analysis of the phenotypic manifestation of inactivation of several genes from the ytlI–ytnM operon containing the ribR gene and results of Northern hybridization showed that the ribR gene does not have the self promoter and is transcribed from the main promoter of the ytlI–ytnM operon. Two sites of single nucleotide substitutions leading to derepression of ribR gene were identified between the putative main promoter and transcription start of the ytlI–ytnM operon regulatory region.

Document Type: Research article

DOI: http://dx.doi.org/10.1023/B:RUGE.0000029163.22026.d0

Affiliations: 1: Department of Molecular and Radiation Biophysics, Konstantinov St. Petersburg Institute of Nuclear Physics, Russian Academy of Sciences, Gatchina, Leningrad oblast, 188350 Russia perumov@lbp.ru, Email: perumov@lbp.ru 2: State Research Institute of Genetics and Selection of Industrial Microorganisms, Moscow, 113545 Russia alexmir@genetika.ru, Email: alexmir@genetika.ru

Publication date: 2004-05-01