Reformatsky reaction of methyl 1-bromocyclohexane-1-carboxylate with N-aryl-2-oxochromene-3-carboxamides
Authors: Shchepin, V.; Kirillov, N.; Vakhrin, M.; Bayanova, O.; Shurov, S.; Silaichev, P.
Source: Russian Journal of General Chemistry, Volume 76, Number 7, July 2006 , pp. 1146-1149(4)
Publisher: MAIK Nauka/Interperiodica
Abstract:Reformatsky reagent generated from methyl 1-bromocyclohexane-1-carboxylate reacted with N-aryl-2-oxochromene-3-carboxamides and N-aryl-6-bromo-2-oxochromene-3-carboxamides to give, depending on the conditions, the corresponding N-aryl-(6-bromo)-4-(1-methoxycarbonylcyclohexyl)-2-oxochroman-3-carboxamides or 3-aryl-(9-bromo)-1,1-pentamethylene-2,3,4,4a,5,10b-hexahydro-1H-chromeno[3,4-c]pyridine-2,4,5-triones. The products were isolated as a single diastereoisomer.
Document Type: Research Article
Publication date: July 2006