Derivatives of Methyl N-[5(6)-(4-Aminophenylsulfanyl)benzimidazol-2-yl]carbamate and Phthalic Anhydrides. Synthesis and Biological Properties

Authors: Pilyugin, V. S.; Mikhailyuk, A. N.; Kosareva, V. M.; Chikireva, G. E.; Kiseleva, G. V.; Kuznetsova, S. L.

Source: Russian Journal of General Chemistry, Volume 74, Number 3, March 2004 , pp. 393-398(6)

Publisher: MAIK Nauka/Interperiodica

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Abstract:

Products of the reactions methyl N-[5(6)-(4-aminophenylsulfanyl)benzimidazol-2-yl]carbamate with phthalic anhydrides, involving the aniline nitrogen atoms, were obtained. Biological properties (embryotoxicity and toxicity) of the products and their mixtures with phase-transfer catalysts were studied. On this basis, new antihelminthic agents were developed.

Document Type: Research Article

DOI: http://dx.doi.org/10.1023/B:RUGC.0000030396.95958.31

Affiliations: Research Technological Institute of Herbicides and Growth Regulators, Academy of Sciences of Bashkortostan, Ufa, Bashkortostan, Russia

Publication date: March 1, 2004

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