Derivatives of Methyl N-[5(6)-(4-Aminophenylsulfanyl)benzimidazol-2-yl]carbamate and Phthalic Anhydrides. Synthesis and Biological Properties
Authors: Pilyugin, V. S.; Mikhailyuk, A. N.; Kosareva, V. M.; Chikireva, G. E.; Kiseleva, G. V.; Kuznetsova, S. L.
Source: Russian Journal of General Chemistry, Volume 74, Number 3, March 2004 , pp. 393-398(6)
Publisher: MAIK Nauka/Interperiodica
Abstract:Products of the reactions methyl N-[5(6)-(4-aminophenylsulfanyl)benzimidazol-2-yl]carbamate with phthalic anhydrides, involving the aniline nitrogen atoms, were obtained. Biological properties (embryotoxicity and toxicity) of the products and their mixtures with phase-transfer catalysts were studied. On this basis, new antihelminthic agents were developed.
Document Type: Research Article
Affiliations: Research Technological Institute of Herbicides and Growth Regulators, Academy of Sciences of Bashkortostan, Ufa, Bashkortostan, Russia
Publication date: March 1, 2004