Reduction of the Edited Domain of the Mitochondrial A6 Gene for ATPase Subunit 6 in Trypanosomatidae

Authors: Kolesnikov A.A.¹; Merzlyak E.M.¹; Bessolitsyna E.A.¹; Fedyakov A.V.¹; Shonian G.²

Source: Molecular Biology, Volume 37, Number 4, July 2003 , pp. 539-543(5)

Publisher: MAIK Nauka/Interperiodica

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Abstract:

The sequence of mitochondrial A6 (MURF4) was compared for several trypanosomatids in order to assess the reduction of the edited domain (ED). The association between the ED reduction and the phylogenetic position of a species proved to be less tight than believed earlier. Compared with digenetic species, monogenetic ones more often displayed ED reduction and had smaller ED.

Keywords: Trypanosomatidae; mitochondrial genome; uridine editing; ATPase subunit 6 gene

Language: English

Document Type: Research article

Affiliations: 1: Biological Faculty, Moscow State University, Moscow, 119992 Russia sasha@protein.bio.msu.su 2: Institut fuer Mikrobiologie und Hygiene, Charite, Campus Mitte Humboldt Universitate, Berlin, D-10098 Germany

Publication date: 2003-07-01