Estradiol and nitric oxide in men over 50 years of age

Authors: Aksoy H.1; Aksoy Y.2; Akçay F.1; Kurtul N.1

Source: International Urology and Nephrology, Volume 32, Number 1, 2000 , pp. 81-83(3)

Publisher: Springer

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Abstract:

We measured the circulatory levels of nitric oxide and estradiol in men over 50 years with esrogenisation findings. We investigated relation between nitric oxide, which is the principal signal for relaxation of vascular smoth muscle cells, and estradiol levels in serum in men over 50 years with estrogenisation. This study included 14 men with (group 1) and 20 without estrogenisation findings (group 2). Mean nitric oxide and estradiol levels were found to be significantly lower in group 2 than group 1. Group 2 had lower levels sex-hormone binding globin and higher both systolic and diastolic blood pressure values than group 1. There was a significant correlation between nitric oxide and estradiol in esrogenisation group.

Keywords: Male; Aging; Nitric oxide; Estradiol

Language: English

Document Type: Regular paper

Affiliations: 1: Department of Biochemistry, Medical School, Atatüurk University, Erzurum, Turkey 2: Department of Urology, Medical School, Atatüurk University, Erzurum, Turkey

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