Pharmaceutical Research

Compartmental Modeling of Transdermal Iontophoretic Transport II: In Vivo Model Derivation and Application
pp. 335-346(12)
Authors: Nugroho, Akhmad Kharis; Della-Pasqua, Oscar; Danhof, Meindert; Bouwstra, Joke A.

Intravenous Hydrophobic Drug Delivery: A Porous Particle Formulation of Paclitaxel (AI-850)
pp. 347-355(9)
Authors: Straub, Julie A.; Chickering, Donald E.; Lovely, Jonathan C.; Zhang, Huimin; Shah, Bhavdeep; Waud, William R.; Bernstein, Howard

A Novel, Lipid-Free Nanodispersion Formulation of Propofol and Its Characterization
pp. 356-361(6)
Authors: Chen, Hongming; Zhang, Zhong; Almarsson, Örn; Marier, Jean-Francois; Berkovitz, Dina; Gardner, Colin R.

A Scalable, Extrusion-Free Method for Efficient Liposomal Encapsulation of Plasmid DNA
pp. 362-372(11)
Authors: Jeffs, Lloyd B.; Palmer, Lorne R.; Ambegia, Ellen G.; Giesbrecht, Cory; Ewanick, Shannon; MacLachlan, Ian

Cross-linked Small Polyethylenimines: While Still Nontoxic, Deliver DNA Efficiently to Mammalian Cells in Vitro and in Vivo
pp. 373-380(8)
Authors: Thomas, Mini; Ge, Qing; Lu, James J.; Chen, Jianzhu; Klibanov, Alexander

A New Class of 5-Fluoro-2-deoxyuridine Prodrugs Conjugated with a Tumor-Homing Cyclic Peptide CNGRC by Ester Linkers: Synthesis, Reactivity, and Tumor-Cell–Selective Cytotoxicity
pp. 381-389(9)
Authors: Zhang, Zhouen; Hatta, Hiroshi; Tanabe, Kazuhito; Nishimot o, Sei-ichi

Bis(carbamoyloxymethyl) Esters of 2,3-Dideoxyuridine 5-monophosphate (ddUMP) as Potential ddUMP Prodrugs
pp. 390-396(7)
Authors: Khan, Saeed R.; Kumar, Srinivas K.; Farquhar, David

Significant Intestinal Excretion, One Source of Variability in Pharmacokinetics of COL-3, a Chemically Modified Tetracycline
pp. 397-404(8)
Authors: Li, Jing; Zhou, Shufeng; Huynh, Hung; Chan, Eli

Acute Changes in Muscle Blood Flow and Concomitant Muscle Damage after an Intramuscular Administration
pp. 405-412(8)
Authors: Ferré, Pierre Jean; Thein, Eckart; Raymond-Letron, Isabelle; Toutain, Pierre-Louis; Lefebvre, Hervé Pierre

Relationship Between Loperamide-Induced Sedative Effect and Digoxin Pharmacokinetics in Healthy Japanese Subjects
pp. 413-418(6)
Authors: Kobayashi, Michiya; Saitoh, Hiroshi; Yamaguchi, Michiko; Saito, Takeshi; Fujita, Hiroyoshi; Suno, Manabu; Matsubara, Kazuo; Aungst, Bruce J.

Pharmacokinetic and Tissue Distribution Mechanism of Mouse Recombinant Heat Shock Protein 70 in Mice
pp. 419-426(8)
Authors: Takemoto, Seiji; Nishikawa, Makiya; Takakura, Yoshinobu

Formulation and Evaluation of Aerosolized Celecoxib for the Treatment of Lung Cancer
pp. 427-439(13)
Authors: Haynes, Alfred; Shaik, Madhu Sudhan; Chatterjee, Abhijit; Singh, M.

Phase Behavior of Amorphous Molecular Dispersions II: Role of Hydrogen Bonding in Solid Solubility and Phase Separation Kinetics
pp. 440-448(9)
Authors: Vasanthavada, Madhav; Tong, Wei-Qin (Tony); Joshi, Yatindra; Kislalioglu, M. Serpil

Isolated Rafts from Adriamycin-Resistant P388 Cells Contain Functional ATPases and Provide an Easy Test System for P-glycoprotein–Related Activities
pp. 449-457(9)
Authors: Bucher, Karsten; Besse, Camille A.; Kamau, Sarah W.; Wunderli-Allenspach, Heidi; Krämer, Stefanie D.

Characterization of Polarized Expression of Point- or Deletion-Mutated Human BCRP/ABCG2 in LLC-PK1 Cells
pp. 458-464(7)
Authors: Takada, Tappei; Suzuki, Hiroshi; Sugiyama, Yuichi

Interaction of the Macrolide Antibiotic Azithromycin with Lipid Bilayers: Effect on Membrane Organization, Fluidity, and Permeability
pp. 465-475(11)
Authors: Berquand, A.; Fa, N.; Dufrêne, Y. F.; Mingeot-Leclercq, M.-P.

Novel Film Modifiers to Alter the Physical Properties of Composite Ethylcellulose Films
pp. 476-489(14)
Authors: Chan, Lai Wah; Ong, Kang Teng; Heng, Paul Wan Sia

Comparative Investigation by Two Analytical Approaches of Enthalpy Relaxation for Glassy Glucose, Sucrose, Maltose, and Trehalose
pp. 490-495(6)
Authors: Kawai, Kiyoshi; Hagiwara, Tomoaki; Takai, Rikuo; Suzuki, Toru

AAPS Update
pp. 496-497(2)