Pharmaceutical Research

Novel Approaches to Vaccine Delivery
pp. 1519-1530(12)
Authors: Derek T. O'Hagan; Rino Rappuoli

Peroxisome Proliferator-Activated Receptor (PPAR)-: A Pharmacological Target with a Promising Future
pp. 1531-1538(8)
Authors: Daniel H. van Raalte; Min Li; P. Haydn Pritchard; Kishor M. Wasan

An Automated Method for the Determination of Montelukast in Human Plasma Using Dual-Column HPLC Analysis and Peak Height Summation of the Parent Compound and Its Photodegradation Product
pp. 1539-1544(6)
Authors: Glenn A. Smith; Cynthia M. Rawls; Robert L. Kunka

Insulin Nanoparticles: A Novel Formulation Approach for Poorly Water Soluble Zn-Insulin
pp. 1545-1553(9)
Authors: Elaine Merisko-Liversidge; Simon L. McGurk; Gary G. Liversidge

The Use of Inverse Phase Gas Chromatography to Study the Glass Transition Temperature of a Powder Surface
pp. 1554-1557(4)
Authors: Graham Buckton; Ameet Ambarkhane; Kim Pincott

Influence of 5-Fluorouracil-Loaded Microsphere Formulation on Efficient Rat Glioma Radiosensitization
pp. 1558-1563(6)
Authors: Valérie-Gaëlle Roullin; Martine Mege; Laurent Lemaire; Jean-Pierre Cueyssac; Marie-Claire Venier-Julienne; Philippe Menei; Erik Gamelin; Jean-Pierre Benoit

Heat-Treated Fungizone Retains Amphotericin B Antifungal Activity Without Renal Toxicity in Rats Infected with Aspergillus Fumigatus
pp. 1564-1566(3)
Authors: Olena Sivak; Karen Bartlett; Kishor M. Wasan

Identification of Biowaivers Among Class II Drugs: Theoretical Justification and Practical Examples
pp. 1567-1572(6)
Authors: Eleni Rinaki; Aristides Dokoumetzidis; Georgia Valsami; Panos Macheras

Design and Evaluation of an Emulsion Vehicle for Paclitaxel. I. Physicochemical Properties and Plasma Stability
pp. 1573-1580(8)
Authors: Jihong Han; Stanley S. Davis; Catherine Papandreou; Colin D. Melia; Clive Washington

Biodegradable Self-Assembling PEG-Copolymer as Vehicle for Poorly Water-Soluble Drugs
pp. 1581-1590(10)
Authors: Louisa Ould-Ouali; Albertina Ariën; Joel Rosenblatt; Aruna Nathan; Patricia Twaddle; Tom Matalenas; Maureen Borgia; Steve Arnold; Daniel Leroy; Mustapha Dinguizli; Laurence Rouxhet; Marcus Brewster; Véronique Préat

The Cohesive-Adhesive Balances in Dry Powder Inhaler Formulations I: Direct Quantification by Atomic Force Microscopy
pp. 1591-1597(7)
Authors: Philippe Begat; David A.V. Morton; John N. Staniforth; Robert Price

Phase Behavior of Amorphous Molecular Dispersions I: Determination of the Degree and Mechanism of Solid Solubility
pp. 1598-1606(9)
Authors: Madhav Vasanthavada; Wei-Qin Tong; Yatindra Joshi; M. Serpil Kislalioglu

Characterization of Suspension-Based Metered Dose Inhaler Formulations Composed of Spray-Dried Budesonide Microcrystals Dispersed in HFA-134a
pp. 1607-1614(8)
Authors: Thomas E. Tarara; Michael S. Hartman; Howard Gill; Alan A. Kennedy; Jeffry G. Weers

Effect of pH, Counter Ion, and Phosphate Concentration on the Glass Transition Temperature of Freeze-Dried Sugar-Phosphate Mixtures
pp. 1615-1621(7)
Authors: Satoshi Ohtake; Carolina Schebor; Sean P. Palecek; Juan J. de Pablo

Metabolism and Disposition of the HIV-1 Protease Inhibitor Lopinavir (ABT-378) Given in Combination with Ritonavir in Rats, Dogs, and Humans
pp. 1622-1630(9)
Authors: Gondi N. Kumar; Venkata K. Jayanti; Marianne K. Johnson; John Uchic; Samuel Thomas; Ronald D. Lee; Brian A. Grabowski; Hing L. Sham; Dale J. Kempf; Jon F. Denissen; Kennan C. Marsh; Eugene Sun; Stanley A. Roberts

Tamoxifen Alters Hepatic Cytochrome P450 Enzyme Expression and Circulating Growth Hormone Levels in Intact Male Rats
pp. 1631-1636(6)
Authors: Ludger M. Ickenstein; Susan L. Holsmer; Stelvio M. Bandiera

Assessment of the Potential Skin Irritation of Lysine-Derivative Anionic Surfactants Using Mouse Fibroblasts and Human Keratinocytes as An Alternative to Animal Testing
pp. 1637-1641(5)
Authors: L. Sanchez; M. Mitjans; M.R. Infante; M.P. Vinardell

Isothermal Titration Calorimetric Study of RNase-A Kinetics (cCMP 3'-CMP) Involving End-Product Inhibition
pp. 1642-1647(6)
Authors: Shawn D. Spencer; Robert B. Raffa

Tryptophan Residues Play an Important Role in the Extraordinarily High Affinity Binding Interaction of UCN-01 to Human -1-Acid Glycoprotein
pp. 1648-1655(8)
Authors: Masaaki Katsuki; Victor Tuan Giam Chuang; Koji Nishi; Ayaka Suenaga; Masaki Otagiri

Polyelectrolyte Nanoparticles Mediate Vascular Gene Delivery
pp. 1656-1661(6)
Authors: Sergey Zaitsev; Régis Cartier; Oleg Vyborov; Gleb Sukhorukov; Bernd-Reiner Paulke; Annekathrin Haberland; Yelena Parfyonova; Vsevolod Tkachuk; Michael Böttger

Application of Novel Solid Lipid Nanoparticle (SLN)-Gene Vector Formulations Based on a Dimeric HIV-1 TAT-Peptide in Vitro and in Vivo
pp. 1662-1669(8)
Authors: Carsten Rudolph; Ulrike Schillinger; Aurora Ortiz; Kerstin Tabatt; Christian Plank; Rainer H. Müller; Joseph Rosenecker

In Vitro and in Vivo Metabolism of the Anti-Cancer Agent CI-1040, a MEK Inhibitor, in Rat, Monkey, and Human
pp. 1670-1679(10)
Authors: Paul A. Wabnitz; David Mitchell; David A.M. Wabnitz

Role of PEPT2 in the Choroid Plexus Uptake of Glycylsarcosine and 5-Aminolevulinic Acid: Studies in Wild-Type and Null Mice
pp. 1680-1685(6)
Authors: Scott M. Ocheltree; Hong Shen; Yongjun Hu; Jianming Xiang; Richard F. Keep; David E. Smith

Interactions of Human P-glycoprotein with Simvastatin, Simvastatin Acid, and Atorvastatin
pp. 1686-1691(6)
Authors: Jerome H. Hochman; Nicole Pudvah; Julia Qiu; Masayo Yamazaki; Cuyue Tang; Jiunn H. Lin; Thomayant Prueksaritanont

Formulation Optimization of Paclitaxel Carried by PEGylated Emulsions Based on Artificial Neural Network
pp. 1692-1697(6)
Authors: Tianyuan Fan; Kozo Takayama; Yoshiyuki Hattori; Yoshie Maitani

An Integrated Model for the Analysis of Pharmacokinetic Data from Microdialysis Experiments
pp. 1698-1707(10)
Authors: Karin Tunblad; Margareta Hammarlund-Udenaes; E. Niclas Jonsson

Early Prediction of Pharmaceutical Oxidation Pathways by Computational Chemistry and Forced Degradation
pp. 1708-1717(10)
Authors: Darren L. Reid; C. Jeffrey Calvitt; Mark T. Zell; Kenneth G. Miller; Carol A. Kingsmill

Letter to Editor: Use of Inverse Gas Chromatography (IGC) to Determine the Surface Energy and Surface Area of Powdered Materials
pp. 1718-1720(3)
Authors: D. Cline; R. Dalby

AAPS Update
pp. 1721-1722(2)

Reviewers for Pharmaceutical Research (Volume 20) for the Period of Novemver 1, 2002 and October 31, 2003
pp. 1723-1724(2)