Theoretical Considerations for the Design and Development of a Drug: Influence of Pharmacokinetics and Dosage Regimen on Receptor Interactions

Authors: Mordenti J.¹; Rescigno A.²

Source: Pharmaceutical Research, Volume 10, Number 5, May 1993 , pp. 777-782(6)

Publisher: Springer

Abstract:

Keywords: antiplatelet drug; association and dissociation constant; efficiency factor; G4120; gpIIb/IIIa; residence time

Language: English

Document Type: Regular paper

Affiliations: 1: Genentech Inc., South San Francisco, California 94080. To whom correspondence should be addressed at Genentech, Inc., 460 Point San Bruno Boulevard, South San Francisco, California 94080. 2: School of Pharmacy, University of Parma, Parma, Italy.

Publication date: 1993-05-01

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• In this Subject: Pharmacology
• By this author: Mordenti J. ;  Rescigno A.

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