Pharmaceutical Research

Behavior of Hygroscopic Pharmaceutical Aerosols and the Influence of Hydrophobic Additives
pp. 1-7(7)
Authors: Hickey A.J.; Martonen T.B.

Mean Residence Time of Oral Drugs Undergoing First-Pass and Linear Reversible Metabolism
pp. 8-13(6)
Authors: Cheng H.; Jusko W.J.

Enantioselective Pharmacokinetics of dl-threo-Methylphenidate in Humans
pp. 14-21(8)
Authors: Srinivas N.R.; Hubbard J.W.; Korchinski E.D.; Midha K.K.

Pharmacokinetics of Stereomeric 1,4:3,6-Dianhydrohexitol Mononitrates in Rats
pp. 22-27(6)
Authors: Tzeng T-B.; Fung H-L.

Steady-State Bioavailability and Day-to-Day Variability of a Multiple-Unit (CR/ZOK) and a Single-Unit (OROS) Delivery System of Metoprolol After Once-Daily Dosing
pp. 28-34(7)
Authors: Sandberg A.; Abrahamsson B.; Svenheden A.; Olofsson B.; Bergstrand R.

Time-Dependent Disposition of -Naphthoflavone in the Rat
pp. 35-43(9)
Authors: Adedoyin A.; Aarons L.; Houston J.B.

Distribution of Tacrine Across the Blood–Brain Barrier in Awake, Freely Moving Rats Using in Vivo Microdialysis Sampling
pp. 44-48(5)
Authors: Telting-Diaz M.; Lunte C.E.

Prinomide Tromethamine Pharmacokinetics: Mutually Dependent Saturable and Competitive Protein Binding Between Prinomide and Its Own Metabolite
pp. 49-55(7)
Authors: Kochak G.M.; Pai S.; Iannucci R.; Honc F.; Kachmar D.; Perrino P.; Egger H.

Column-Switching High-Performance Liquid Chromatographic Determination of a 2-Pyridinone-Based Human Immunodeficiency Virus Type 1 (HlV-l)-Specific Reverse Transcriptase Inhibitor in Human Plasma
pp. 56-60(5)
Authors: Woolf E.J.; Matuszewski B.K.

Changes in Material Properties Accompanying the National Formulary (NF) Identity Test for Microcrystalline Cellulose
pp. 61-67(7)
Authors: Brittain H.G.; Lewen G.; Newman A.W.; Fiorelli K.; Bogdanowich S.

Prodrugs of Peptides. 18. Synthesis and Evaluation of Various Esters of Desmopressin (dDAVP)
pp. 68-74(7)
Authors: Kahns A.H.; Buur A.; Bundgaard H.

The 3-Keto–Diol Equilibrium of Trospectomycin Sulfate Bulk Drug and Freeze-Dried Formulation: Solid-State Carbon-13 Cross-Polarization Magic Angle Spinning (CP/MAS) and High-Resolution Carbon-13 Nuclear Magnetic Resonance (NMR) Spectroscopy Studies
pp. 75-79(5)
Authors: Likar M.D.; Taylor R.J.; Fagerness P.E.; Hiyama Y.; Robins R.H.

Design of New Formulations for Topical Ocular Administration: Polymeric Nanocapsules Containing Metipranolol
pp. 80-87(8)
Authors: Losa C.; Marchal-Heussler L.; Orallo F.; Jato J.L.V.; Alonso M.J.

Compression Characteristics of Granulated Materials. VII. The Effect of Intragranular Binder Distribution on the Compactibility of Some Lactose Granulations
pp. 88-94(7)
Authors: Wikberg M.; Alderborn G.

Chemical Pathways of Peptide Degradation. IV. Pathways, Kinetics, and Mechanism of Degradation of an Aspartyl Residue in a Model Hexapeptide
pp. 95-102(8)
Authors: Oliyai C.; Borchardt R.T.

Stability of -Galactosidase, a Model Protein Drug, Is Related to Water Mobility as Measured by ^17O Nuclear Magnetic Resonance (NMR)
pp. 103-108(6)
Authors: Yoshioka S.; Aso Y.; Izutsu K-i.; Terao T.

Controlled Delivery of Pilocarpine. 1. In Vitro Characterization of Gelfoam^® Matrices
pp. 109-112(4)
Authors: Nadkarni S.R.; Yalkowsky S.H.

Comparison of the Permeability Characteristics of a Human Colonic Epithelial (Caco-2) Cell Line to Colon of Rabbit, Monkey, and Dog Intestine and Human Drug Absorption
pp. 113-118(6)
Authors: Rubas W.; Jezyk N.; Grass G.M.

Sustained Bronchodilation with Isoproterenol Poly(Glycolide-co-Lactide) Microspheres
pp. 119-125(7)
Authors: Lai Y-L.; Mehta R.C.; Thacker A.A.; Yoo S-D.; McNamara P.J.; DeLuca P.P.

Human Transbuccal Absorption of Diclofenac Sodium from a Prototype Hydrogel Delivery Device
pp. 126-129(4)
Authors: Cassidy J.; Berner B.; Chan K.; John V.; Toon S.; Holt B.; Rowland M.

Regional Gastrointestinal Absorption of the Beta-Blocker Pafenolol in the Rat and Intestinal Transit Rate Determined by Movement of ^14C-Polyethylene Glycol (PEG) 4000
pp. 130-135(6)
Authors: Lennernäs H.; Regårdh C-G.

Relationship Among Physicochemical Properties, Skin Permeability, and Topical Activity of the Racemic Compound and Pure Enantiomers of a New Antifungal
pp. 136-140(5)
Authors: Wearley L.; Antonacci B.; Cacciapuoti A.; Assenza S.; Chaudry I.; Eckhart C.; Levine N.; Loebenberg D.; Norris C.; Parmegiani R.; Sequeira J.; Yarosh-Tomaine T.

Acacia-Gelatin Microencapsulated Liposomes: Preparation, Stability, and Release of Acetylsalicylic Acid
pp. 141-146(6)
Authors: Dong C.; Rogers J.A.

Comparison of the Leakage of Carboxyfluorescein from Symmetric-and Asymmetric-Acyl Chain Phosphatidylcholine Vesicles
pp. 147-151(5)
Authors: Wiedmann T.S.; Salmon A.; Perkins W.R.

Effect of Humidity and Occlusion on the Percutaneous Absorption of Parathion in Vitro
pp. 152-155(4)
Authors: Chang S-K.; Riviere J.E.

Kinetics of Aspirin Hydrolysis and Stabilization in the Presence of 2-Hydroxypropyl--Cyclodextrin
pp. 156-159(4)
Authors: Choudhury S.; Mitra A.K.

Reviewers for Pharmaceutical Research (October 1, 1991-October 19, 1992)
pp. 160-161(2)

European Reviewers for Pharmaceutical Research (October 1991-October 1992)
pp. 162-162(1)

Japanese Reviewers for Pharmaceutical Research (May 1992-September 1992)
pp. 162-162(1)

Association News and Announcements
pp. 163-163(1)

HANS BUNDGAARD IN MEMORIAM
pp. 164-164(1)
Authors: Kristensen H.G.; Breimer D.D.