Histological Esophagitis Before and After Surgical Treatment of Morbid Obesity (Capella Technique): A Prospective Study
Source: Obesity Surgery, Volume 18, Number 4, April 2008 , pp. 367-370(4)
Abstract:The effects of vertical banded gastroplasty/Roux-en-Y gastric bypass (Capella) on the esophageal mucosa of patients with histological esophagitis are poorly understood. To evaluate long-term effects, we investigated the persistence, aggravation or disappearance of histological esophagitis in patients with morbid obesity and reflux esophagitis (diagnosed by endoscopic biopsy) after Roux-en-Y gastric bypass.
Twenty-one patients with morbid obesity and esophagitis (histological diagnosis) were submitted to gastric bypass (Fobi-Capella technique) and underwent upper endoscopy and esophageal biopsy during the late postoperative period.
The mean age of the patients was 42.57 ± 7.49 years (30 to 56). Nineteen (90.48%) patients were women, and two (9.52%) were men. Before surgery, the patients presented a mean weight of 124.26 ± 19.09 kg and a mean body mass index (BMI) of 48.46 ± 6.37 kg/m2. Thirteen (61.90%) patients had endoscopic esophagitis before surgery. The mean weight and BMI were 81.65 ± 13.16 kg and 31.91 ± 4.99 kg/m2, respectively, during the late postoperative period (29.80 ± 8.91 months). The mean percentage of excess weight loss was 68.7 ± 14.6%. Among the 21 patients with a preoperative histological diagnosis of reflux esophagitis, five (23.18%) had the same diagnosis after surgery, and four (19.04%) continued to present findings of endoscopic esophagitis.
Vertical banded gastroplasty/Roux-en-Y gastric bypass (Capella technique) is effective in the treatment of reflux esophagitis. No association was observed between the percentage of excess weight loss and improvement of esophagitis.
Document Type: Research Article
Affiliations: 1: Santa Casa de Misericórdia de Belo Horizonte, Universidade Federal de Minas Gerais, Av.Contorno, 4747, sala 1108-1109, 30110-090, Belo Horizonte, MG, Brazil, Email: firstname.lastname@example.org 2: Santa Casa de Misericórdia de Belo Horizonte, Universidade Federal de Minas Gerais, Av.Contorno, 4747, sala 1108-1109, 30110-090, Belo Horizonte, MG, Brazil
Publication date: April 1, 2008