Neuro-vascular central nervous recording/stimulating system: Using nanotechnology probes

Authors: Llinás, Rodolfo¹; Walton, Kerry²; Nakao, Masayuki³; Hunter, Ian⁴; Anquetil, Patrick⁴

Source: Journal of Nanoparticle Research, Volume 7, Number 2, June 2005 , pp. 111-127(17)

Publisher: Springer

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Abstract:

Electrical recording from spinal cord vascular capillary bed has been achieved demonstrating that the intravascular space may be utilized as a means to address brain activity with out violating the brain parenchyma. While the initial demonstration was implemented using electrically insulated platinum electrodes in vitro, the possibility of using conducting polymer filaments is now being explored. This paper presents a set of highly possible future scenarios where the integration of electrophysiology and novel polymer technology may serve as a new approach towards basic and medical neuroscience.

Keywords: brain research; electrical recording; neural stimulation; biocompatibility; nanowires; conducting polymers; nanobiomedicine; nanobiotechnology

Document Type: Research article

DOI: http://dx.doi.org/10.1007/s11051-005-3134-4

Affiliations: 1: Department of Physiology and Neuroscience, NYU School of Medicine, 550 1st Av., New York, NY, 10016, USA, Email: llinar01@popmail.med.nyu.edu 2: Department of Physiology and Neuroscience, NYU School of Medicine, 550 1st Av., New York, NY, 10016, USA, 3: Institute of Engineering Innovation, University of Tokyo, Japan, 4: Department of Mechanical Engineering, BioInstrumentation Laboratory, Massachusetts Institute of Technology, USA,

Publication date: 2005-06-01