Neuropathology and Molecular Studies of a Patient with Tourette Syndrome and Huntington Disease
Authors: Burd, L.; Kerbeshian, J.; Meredith, J.L.
Source: Journal of Developmental and Physical Disabilities, Volume 09, Number 3, September 1997 , pp. 255-263(9)
This paper reviews the association of Huntington's Disease (HD) and tic disorder or Tourette Syndrome (TS) We also present the results of a follow-up study of a male with childhood-onset TS and adult-onset HD who died at 45 years of age. The developmental course and results of neuropathologic and molecular studies of this patient are reported. This is the first case of childhood onset of TS with adult onset of HD reported who has come to autopsy. A developmental model for childhood and adult neuropsychiatric disorders is presented.
Document Type: Research Article
Affiliations: Department of Neuroscience and The Child Evaluation and Treatment Program, University of North Dakota School of Medicine, Grand Forks, North Dakota 58202
Publication date: 1997-09-01