Synthesis and structure of 2-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalene)]-5-benzimidazole ethylcarboxylate monohydrate
Source: Journal of Chemical Crystallography, Volume 30, Number 2, February 2000 , pp. 103-107(5)
As part of a program investigating the conformations of potential anticarcinogens and antioxidants, the structure of the title compound C_24H_28N_2O_2·H_2O is reported. The monohydrate crystallizes in the monoclinic space group P2/c with unit cell parameters a = 16.184(1),b = 7.937(1), c = 16.968(1), = 92.788(7)°, and Z = 4. The benzimidazole and tetrahydrotetramethylnaphthalene ring systems are inclined to one another by approximately 26°. The water molecule plays an important role in the crystal structure by hydrogen bonding to different functional groups of three organic moieties. Additional crystal stabilization is dueto stacking of benzimidazole rings.
Document Type: Regular paper
Affiliations: 1: Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Tandogan 06100, Ankara, Turkey 2: Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa
Publication date: 2000-02-01