Crystal structure of the cytotoxic marine alkaloid 2-bromoleptoclinidinone

Authors: Lindsay, B.S.; Oliver, A.G.; Rickard, C.E.F.; Copp, B.R.

Source: Journal of Chemical Crystallography, Volume 28, Number 8, August 1998 , pp. 645-648(4)

Publisher: Springer

Buy & download fulltext article:


Price: $47.00 plus tax (Refund Policy)


2-Bromoleptoclinidinone methanol solvate, C18H8BrN3O·CH4O, crystallizes in the orthorhombic space group Pbca with a = 15.7013(2), b = 7.3308(1), and c = 26.9326(1) Å. The molecule is essentially planar, with the largest deviations occurring at bromine (-0.21 Å), carbonyl oxygen O(l) (+0.19 Å) and in ring-A (C(9) -0.15 Å, C(10) -0.15 Å). Methanol occupies the 1,10-phenanthroline-like metal binding site of the title compound.

Keywords: 2-Bromoleptoclinidinone; crystal structure; cytotoxic; marine alkaloid

Document Type: Research Article

Affiliations: Department of Chemistry, University of Auckland, Private Bag 92019, Auckland, New Zealand

Publication date: August 1, 1998

Related content


Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content

Text size:

A | A | A | A
Share this item with others: These icons link to social bookmarking sites where readers can share and discover new web pages. print icon Print this page