Identification of AD/HD Subtypes Using Laboratory-Based Measures: A Cluster Analysis

Authors: Marks D.J.¹; Himelstein J.¹; Newcorn J.H.²; Halperin J.M.³

Source: Journal of Abnormal Child Psychology, Volume 27, Number 2, April 1999 , pp. 167-175(9)

Publisher: Springer

Abstract:

The current investigation used laboratory-based measures of inattention, impulsivity, and activity level to identify subgroups of children with attention-deficit/hyperactivity disorder (AD/HD). Data derived from solid state actigraphs and a continuous performance test (CPT) were obtained from a clinically referred sample and submitted to a cluster analysis. These empirically derived groups were then evaluated for clinical relevance and subsequently validated by parent and teacher ratings and tests of intellectual functioning and academic achievement. Four distinct subgroups emerged: Hyperactive-inattentive (HYP-IN), impulsive-inattentive (IMP-IN), inattentive only, and hyperactive only. The HYP-IN group was impaired on measures of intellectual functioning and academic achievement relative to the other three groups. In contrast, the IMP-IN group was generally rated as more aggressive, although this difference was not statistically significant for all measures. The data suggest that the augmentation of clinical descriptors with laboratory-based data may be an effective strategy by which to categorize diagnostic subgroups of AD/HD.

Keywords: Attention-deficit/hyperactivity disorder; laboratory-based measures; diagnosis; classification

Language: English

Document Type: Research article

Affiliations: 1: Neuropsychology Doctoral Subprogram, Graduate School and University Center of the City University of New York, New York, New York 2: Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 3: Neuropsychology Doctoral Subprogram, Graduate School and University Center of the City University of New York, New York, New York. Department of Psychiatry, Mount Sinai School of Medicine, New York, New York. Jeffrey M. Halperin, Department of Ps

Publication date: 1999-04-01

• In this: publication
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• In this Subject: Neurology & Psychiatry ,  Pediatrics
• By this author: Marks D.J. ;  Himelstein J. ;  Newcorn J.H. ;  Halperin J.M.

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