Dialysis efficacy and nutritional status in elderly hemodialyzed patients

Authors: Hiroshige K.¹; Kabashima N.¹; Kanegae K.¹; Mutoh Y.²; Ohtani A.²; Takasugi M.¹; Kuroiwa A.¹

Source: Geriatric Nephrology and Urology, Volume 6, Number 3, 1997 , pp. 149-158(10)

Publisher: Springer

Abstract:

To examine the effect of dialysis efficacy on nutritional status. Prospective, nonrandomized comparison study over a 24-month period. Sixty-nine chronic hemodialysis patients (36 patients aged over 65 (elderly) and 33 aged under 64 (young). Each group was further divided into three subgroups according to the level of dialysis dose shown by Kt/V urea. The malnutrition index (MI) based on seven nutritional parameters and estimated protein calorie intakes based on urea kinetics were determined. In subgroup 0 (i.e. patients with persistently high Kt/V urea, mean 1.3), the MI improved with time in the young (from 26.8 to 25.2, p < 0.01) but not in the elderly (from 29.2 to 30.4, ns). In subgroup 1 (i.e. patients whose Kt/V urea increased from 1.0 to over 1.3), the MI improved significantly in the young from 28.1 to 25.2 (p < 0.01) concomitantly with an increase in the estimated dietary protein and calorie intakes, but not in the elderly (from 30.3 to 29.9, ns). In subgroup 2 (i.e. patients who had persistent low Kt/V urea, mean 1.0), the MI score further deteriorated in the elderly (from 30.8 to 32.8, p < 0.01) and young (from 28.5 to 30.7, ns). Increasing the dialysis dose as a treatment for malnutrition does not necessarily improve nutritional status in malnourished elderly patients, but it does in young individuals, possibly because of the additional adverse effect of aging on nutrition.

Keywords: hemodialysis; malnutrition; elderly patient; urea kinetics

Language: English

Document Type: Regular paper

Affiliations: 1: 2nd Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu City, Fukuoka 807, Japan 2: Department of Internal Medicine, Chikuho Hospital, 675-1 Yamabe, Nougata City, Fukuoka 822, Japan

Publication date: 1997-01-01

• In this: publication
• By this: publisher
• In this Subject: Internal Medicine ,  Urology
• By this author: Hiroshige K. ;  Kabashima N. ;  Kanegae K. ;  Mutoh Y. ;  Ohtani A. ;  Takasugi M. ;  Kuroiwa A.

Website © Publishing Technology. Article copyright remains with the publisher, society or author(s) as specified within the article.

• Terms and conditions
• Privacy policy
• Information for advertisers